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Mechanical Abnormalities of the Airway Wall in Adult Mice After Intrauterine Growth Restriction

We propose that mechanical abnormalities of the airway wall acquired through disrupted fetal growth impact susceptibility to disease

Nicotine and other potentially harmful compounds in "nicotine-free" e-cigarette liquids in Australia

The aim of our investigation was to assess the chemical composition of a range of e-liquids available in Australia, focusing on nicotine and other po…

Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams

While maternal high fat diet compromised litter survival, it also promoted somatic and lung growth (increased lung volume) in the offspring

Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation

These data provide proof of concept supporting the rationale for developing transplacental immune reprogramming approaches for primary disease preven…

Directing immune development to curb sky-rocketing disease

Once upon a time it was infectious diseases like polio, measles or tuberculosis that most worried parents. With these threats now largely under contr…

Effects of human rhinovirus on epithelial barrier integrity and function in children with asthma

This study demonstrates novel intrinsic differences in tight junctions gene and protein expression between airway epithelial cells of children with a…

Independent and combined effects of airway remodelling and allergy on airway responsiveness

There was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the…

Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells

Apically located tight junctions in airway epithelium perform a fundamental role in controlling macromolecule migration through paracellular spaces.

Foetal growth restriction in mice modifies postnatal airway responsiveness in an age and sex-dependent manner

Our data demonstrate changes in airway responsiveness as a result of intrauterine growth restriction that could influence susceptibility to asthma de…

Fragranced consumer products: effects on asthmatic Australians

Most asthmatics would prefer workplaces, healthcare facilities, and environments that are fragrance-free, which could help reduce adverse effects