Epigenetically regulated genes have a great theranostic potential, especially in tumors with no apparent driver mutations.
CAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell popul…
We provided a broad atlas of miRNA expression and promoters in primary mammalian cells, establishing a foundation for detailed analysis of miRNA.
Our results suggest a complex but highly coordinated regulation of adipogenesis
Identified romidepsin as a promising therapeutic for mixed lineage leukemia (MLL)-rearranged infant acute lymphoblastic leukemia
SlideBase, a web tool which offers a new way of selecting genes, promoters, enhancers and microRNAs that are preferentially expressed/used in a speci…
The aim of the Translational Intelligence team is to understand how individual bases in our genome predispose, alter and interact in normal and disea…
Feilman Fellow; Head, Precision Health Research and Head, Translational Intelligence
CAGEd-oPOSSUM can identify transcription factors that act as key regulators of genes involved in specific mammalian cell and tissue types
Children who were born with reduced gestational age, birthweight, and birth length have persistently increased rates of infection-related admissions…