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Role of COL5A1 in lung squamous cell Carcinoma: Prognostic Implications and therapeutic potential

Lung squamous cell carcinoma (LUSC) is a significant health concern, characterized by a lack of specific therapies and limited treatment options for patients in advanced stages. This study aims to identify key molecules of prognostic importance in LUSC and provide an experimental foundation for their potential therapeutic applications.

Echocardiographic predictors of surgical outcomes in pulmonary atresia with intact ventricular septum and development of a discriminatory calculator

Pulmonary atresia with intact ventricular septum is a rare congenital cardiac lesion with significant anatomical heterogeneity. Surgical planning of borderline cases remains challenging and is primarily based on echocardiography. The aim was to identify echocardiographic parameters that correlate with surgical outcome and to develop a discriminatory calculator.

IDH-mutant gliomas in children and adolescents - from biology to clinical trials

Gliomas account for nearly 30% of all primary central nervous system (CNS) tumors in children and adolescents and young adults (AYA), contributing to significant morbidity and mortality. The updated molecular classification of gliomas defines molecularly diverse subtypes with a spectrum of tumors associated with age-distinct incidence.

Impact: Research Translation

On this Research Impact page, learn about our work that's actively translated as Government policy or in active practice. Learn how our research is making a difference in people's lives - not tomorrow, next week, or next year - but today!

Multigenerational Familial and Environmental Risk for Autism (MINERvA) Network

The MINERvA Network will allow more accurate and precise determination of the contributions of familial and environmental factors to the etiology of autism.

Microscopy and Imaging

The Kids Research Institute Australia is equipped with a diverse range of histology and microscopy equipment and analysis software to facilitate state-of-the-art imaging.

Screen time study reveals kids missing out on language development

Toddlers exposed to screen time at home are hearing fewer words and making fewer vocalisations, findings from the first longitudinal study to measure the relationship between family screen use and children’s language development have shown.

Wellbeing partnership building resilience after medical trauma

Helping children build resilience and cope with the trauma associated with medical emergencies and chronic health conditions is the focus of a promising pilot program being undertaken by The Kids Research Institute Australia.

Modelling for the health of our next generation

Nearly 170 years ago a British doctor applied geospatial mapping to identify the source of a cholera outbreak in central London.

Research offers new hope for babies with rare leukaemia

A pilot clinical study has found an immunotherapy drug can dramatically increase survival rates for babies with a rare form of leukaemia, paving the way for a major international clinical trial.