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Research

Increased allergic immune response to Sarcoptes scabiei antigens in crusted versus ordinary scabies

Scabies, a parasitic skin infestation by the burrowing "itch" mite Sarcoptes scabiei, causes significant health problems for children and adults worldwide.

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Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation

These data provide proof of concept supporting the rationale for developing transplacental immune reprogramming approaches for primary disease prevention

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Trajectories of childhood immune development and respiratory health relevant to asthma and allergy

Our findings demonstrate the utility of unsupervised analysis in elucidating heterogeneity in asthma pathogenesis

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After asthma: Redefining airways diseases

Identify entrenched areas of asthma management and treatment in which progress has stalled and to challenge current principles

News & Events

Landmark language study draws to a close - but the work is just beginning

A joint initiative between The Kids Research Institute Australia, The University of Western Australia, the University of Kansas and Nebraska University, it is the world’s only study to conduct such a detailed assessment of language and literacy development from infancy through the formative adolescent years.

Research

Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life

Appropriate innate immune function is essential to limit pathogenesis and severity of severe lower respiratory infections (sLRI) during infancy, a leading cause of hospitalization and risk factor for subsequent asthma in this age group.

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Risk factors and prognosis of recurrent wheezing in Chinese young children: A prospective cohort study

We aimed to investigate the risk factors for different wheezing phenotypes in Chinese young children and to explore the prognosis of recurrent wheezing

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Bright Tomorrows Start Today (Parent App)

The Bright Tomorrows app developed at The Kids Research Institute Australia aims to assist parents of children aged 0-5 years to support their child to develop the building blocks of several essential life skills.

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Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype

Previous analyses of family data from the Tasmanian Longitudinal Health Study provide evidence that this phenotype has a stronger genetic cause than asthma...

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Combatting the Normalisation of Sports Gambling and Aggressive Marketing Tactics that Compromise the Mental Health and Wellbeing of Australian Youth

Sports gambling has become increasingly normalised among young people, with the proliferation of sponsorship deals and a 300% rise in the number of gambling advertisements in the past 7 years.

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Comparison of neonatal T regulatory cell function in Papua New Guinean and Australian newborns

We compared neonatal T reg from children born in western conditions (Australia) with those of neonates born in high microbial conditions (Papua New Guinea)...

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Effectiveness of childcare centre interventions to increase young children’s physical activity

The aim of this project is to evaluate the efficacy of childcare centre based interventions to increase young children’s physical activity.

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Social Ventures Australia Evidence Summaries

A series of 12 Australasian Research Summaries were generated by CoLab for the Evidence for Learning website in partnership with Edith Cowan University and Fraser Mustard Centre.

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The Impact of Unfavourable Climatic Conditions on Children and Families

This project aims to explore the impacts of unfavourable climatic conditions on children and families.

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Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study

Atopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children.

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Predicting regional and temporal incidence of RSV and influenza hospitalizations in a birth cohort of young Australian children

Western Australia experiences multiple climatic zones, influencing the epidemiology of respiratory viruses. We aimed to estimate the true incidence of respiratory syncytial virus and influenza hospitalizations across these different climatic regions using predictive modelling.