Search
Research
Developmental Mismatch Across Brain Modalities in Young ChildrenBrain development during the preschool period is complex and extensive and underlies ongoing behavioral and cognitive maturation. Increasing understanding of typical brain maturation during this time is critical to early identification of atypical development and could inform treatments and interventions.
Research
Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infectionsKnowledge gaps regarding human immunity to Streptococcus pyogenes have impeded vaccine development. To address these gaps and evaluate vaccine candidates, we established a human challenge model of S. pyogenes pharyngitis. Here, we analyse antibody responses in serum and saliva against 19 antigens to identify characteristics distinguishing 19 participants who developed pharyngitis and 6 who did not.
Research
Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomesIn this rhinovirus study, we first hypothesized that ex vivo human cells response to virus can serve as a proxy for otherwise controversial in vivo human...
Research
Impact of adolescent peer aggression on later educational and employment outcomes in an Australian cohortThis study used prospective birth cohort data to analyse the relationship between peer aggression at 14 years of age and educational and employment outcomes...
Research
The Immune Response to Skin Trauma Is Dependent on the Etiology of Injury in a Mouse Model of Burn and Excision.This article investigates the impact of burn & excisional injury on the immune system.
Research
Prevalence and patterns of alcohol use in pregnancy in remote Western Australian communities: The Lililwan ProjectAlcohol use in pregnancy is thought to be common in remote Australian communities, but no population-based data are available.
Research
Evolution, Evidence and Effect of Secondary Prophylaxis Against Rheumatic FeverThe association between group A streptococcal infection and rheumatic fever (RF) was established in the early 20th century.
Research
Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studiesPregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to...
Research
Ahead of consensus: A paediatric antifungal prophylaxis censusTo contextualise the ‘Australian & New Zealand Antifungal Consensus Guidelines, 2014, researchers surveyed current routine primary antifungal prophylaxis.
Research
Outcomes of nontransitioned cases in a sample at ultra-high risk for psychosis.Two-thirds of individuals identified as at ultra-high risk for psychosis do not develop psychotic disorder over the medium term.