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Respiratory Syncytial Virus Vaccination during Pregnancy and Effects in InfantsA multi-country randomized, placebo-controlled trial of the safety, immunogenicity and efficacy of respiratory syncytial virus (RSV) F-protein nanoparticle vaccine was undertaken in 4,636 pregnant women and their infants. RSV F-protein vaccine was safe and immunogenic in the pregnant women inducing anti-F IgG, palivizumab-competing antibodies and RSV neutralizing antibodies that were transferred to the fetus.
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Factors associated with pneumococcal carriage and density in children and adults in Fiji, using four cross-sectional surveysThis study describes predictors of pneumococcal nasopharyngeal carriage and density in Fiji
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SmartStartAllergy: a novel tool for monitoring food allergen introduction in infantsInfant feeding practices in Australia have changed over the past decade; a large majority of infants are now fed peanut before 12 months of age
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Delivering Elder- and Community-Led Aboriginal Early Childhood Development Research: Lessons from the Ngulluk Koolunga Ngulluk Koort ProjectWe describe the application of a participatory action research methodology that is grounded in Aboriginal worldviews
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Meta-taxonomic analysis of prokaryotic and eukaryotic gut flora in stool samples from visceral leishmaniasis cases and endemic controls in Bihar State IndiaWe evaluate a meta-taxonomic approach to determine the composition of prokaryotic and eukaryotic gut microflora using sequencing of 16S RNA and 18S rRNA
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Effectiveness of rotavirus vaccines in an Australian population: A case-control studyRV1 and RV5 were both effective in preventing laboratory confirmed and notified rotavirus infections among children aged <5 years
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Malt1 deficient mice develop osteoporosis independent of osteoclast-intrinsic effects of Malt1 deficiencyMalt1 deficient mice develop an osteoporotic phenotype with increased osteoclastogenesis in vivo, but suggest that this is caused by inflammation
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A role for affectivity in rapid facial mimicry: An electromyographic studyUsing a novel methodological approach, these findings provide evidence for the contention that affective processing underlies rapid facial mimicry reactions
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Maternal Smoking During Pregnancy Induces Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic RiskThis study demonstrates a critical timing of cigarette smoke exposure over the life course for establishing persistent changes in DNA methylation into adolescence
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Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing childrenBacterial airway microbiome is highly variable in early life and its role in wheeze remains less clear than viral influences