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Research
Relationship between cytokine expression patterns and clinical outcomes: two population-based birth cohortsOur findings suggest that positive HDM 'allergy tests' and asthma are associated with a broad range of immunophenotypes, which may have important...
Research
Genetic polymorphism of KIR2DL4 (CD158d), a putative NK cell receptor for HLA-G, does not influence susceptibility to asthmaNo reproducible associations with KIR2DL4 genotype were identified, leading us to conclude that the KIR2DL4 9A/10A polymorphism has no influence...
Research
Reversible Control by Vitamin D of Granulocytes and Bacteria in the Lungs of Mice: An Ovalbumin-Induced Model of Allergic Airway DiseaseVitamin D may be essential for restricting the development and severity of allergic diseases and asthma, but a direct causal link between vitamin D...
Research
Immune modulation by UV: Role of vitamin DIn this chapter, evidence for and evidence against the involvement of vitamin D in the immunoregulatory properties of UV radiation is presented.
Research
House dust allergy and immunotherapyHDM allergy is associated with asthma, allergic rhinitis and atopic dermatitis.
Research
Virus infection and allergy in the development of asthma: What is the connection?Information is accumulating which implicates airway inflammation resulting from respiratory viral infections, acting against a background of atopy.
Research
Risk factors for bronchial hyperresponsiveness in teenagers differ with sex and atopic statusSex-related differences in bronchial hyperresponsiveness (BHR) have been reported in adolescents, but the mechanisms remain obscure.
Research
Targeting the mucosal immune system in a pregnant mouse model to prevent experimental allergic airways disease in the offspringStudies in Europe show exposure of pregnant women to high levels of microbial products stimulate immune function maturation in their offspring
Research
The cellular effects of estrogen on allergic asthmaThe study aims to identify the mechanism for this so that this knowledge can be used to better treat asthma and allergies in both males and females.
Research
Mechanisms of IgE sensitizationThis project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.