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Research
Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary diseaseChronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function
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Understanding the aetiology and resolution of chronic otitis media from animal and human studiesThis Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition
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Astrofood, Priorities and Pandemics: Reflections of an Ultra-Processed Breakfast Program and Contemporary Dysbiotic DriftThe United Nation, recognizing the importance of nutrition as a part of the challenges faced by humanity, and declared 2016-2025 the decade of nutrition.
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Down to Earth: Planetary Health and Biophilosophy in the Symbiocene EpochAdvances in science have illuminated the role of the “ecological theatre”—the total living environment—in human health
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Airway surface liquid pH is not acidic in children with cystic fibrosisModulation of ASL pH has been proposed as a therapy for CF. However, evidence that ASL pH is reduced in CF is limited and conflicting.
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World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): PrebioticsDevelop evidence-based recommendations about the use of prebiotics in the prevention of allergy
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Sugar sweetened beverage consumption by Australian children: Implications for public health strategyHigh consumption of sugar sweetened beverages (SSBs) has been linked to unhealthy weight gain and nutrition related chronic disease.
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Maternal diet during breastfeeding: Could it influence food allergy risk in children?Human milk is rich in immuno-modulatory factors that have the potential to shape immune development and influence allergy risk in children. In this article, we describe how breast milk may contribute to making the infant less prone to developing allergies.
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Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczemaElevated egg-specific Th2 cytokine responses were established prior to egg ingestion at 4months and were not significantly altered by introduction of egg
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Early Nutrition as a Major Determinant of 'Immune Health': Implications for Allergy, Obesity and Other Noncommunicable DiseasesA better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases