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Fuel feedstock determines biodiesel exhaust toxicity in a human airway epithelial cell exposure modelBiodiesel is promoted as a sustainable replacement for commercial diesel. Biodiesel fuel and exhaust properties change depending on the base feedstock oil/fat used during creation. The aims of this study were, for the first time, to compare the exhaust exposure health impacts of a wide range of biodiesels made from different feedstocks and relate these effects with the corresponding exhaust characteristics.
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Nicotine and other potentially harmful compounds in "nicotine-free" e-cigarette liquids in AustraliaThe aim of our investigation was to assess the chemical composition of a range of e-liquids available in Australia, focusing on nicotine and other potentially harmful compounds
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Mechanical Abnormalities of the Airway Wall in Adult Mice After Intrauterine Growth RestrictionWe propose that mechanical abnormalities of the airway wall acquired through disrupted fetal growth impact susceptibility to disease
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The concentration of iron in real-world geogenic PM10 is associated with increased inflammation and deficits in lung function in miceMineral dusts in the occupational setting are associated with poor lung health, however very little is known about the impact of heterogeneous community...
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Increased heterogeneity of airway calibre in adult rats after hypoxia-induced intrauterine growth restrictionThe rat model demonstrates that intrauterine growth restriction leads to a more heterogeneous distribution of airway lumen calibre in adulthood
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Rhinovirus exacerbates house-dust-mite induced lung disease in adult miceIn this study, we combined human-rhinovirus infection with a clinically relevant mouse model of aero-allergen exposure using house-dust-mite in an attempt to...
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Acute diesel exhaust particle exposure increases viral titre and inflammation associated with existing influenzaExposure to diesel exhaust particles (DEP) is thought to exacerbate many pre-existing respiratory diseases.
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The influence of moving walls on respiratory aerosol deposition modellingThis work initially examines particle deposition in a Weibull-type geometry, comparing traditional computational fluid dynamics approaches with a novel...
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Chronic carbon dioxide exposure: an unrecognised health risk of climate change?Alexander Larcombe BScEnv (Hons) PhD Honorary Research Fellow Honorary Research Fellow Associate Professor Alexander Larcombe began work at The Kids
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Understanding how viral infection in early life impacts on lung function in adulthoodAlexander David Deborah Larcombe Martino Strickland BScEnv (Hons) PhD BSc PhD PhD Honorary Research Fellow Head, Chronic Diseases Research Program