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HOMEFREE: Scaling-Up Evidence-Based Guidelines for IV-to-Oral Antibiotic Switch in Hospitalised Children, an Implementation Study Protocol

Around half of children admitted to hospital receive intravenous antibiotics, contributing to higher costs, vascular access complications and longer…

Paediatric anaesthesia and the developing brain

Concerns persist regarding the potential long-term effects of general anaesthesia on brain development in children. This narrative review summarises…

Long-term outcomes of childhood encephalitis in Australia: burden and predictors from the Australian childhood encephalitis (ACE) prospective multicentre cohort

Encephalitis is inflammation of the brain parenchyma with heterogenous aetiology and presentation. In children, it often leads to short-term residual…

Restricting outdoor advertising of unhealthy food: feasibility of using a nutrition classification system in Australia

Exposure to food advertising is associated with consumption. Globally, most outdoor food advertisements feature unhealthy foods or beverages. As Aust…

Optimising Asparaginase Use and Managing Hypersensitivity in Australasia—A Clinical Practice Guideline From the Australian and New Zealand Children's Haematology/Oncology Group

Asparaginase is a critical component of modern multi-agent chemotherapy regimens for paediatric acute lymphoblastic leukaemia and lymphoblastic lymph…

Single-cell RNA sequencing profiles drug activity within spatially engineered 3D cultures

Spatial transcriptomic techniques provide a wealth of information useful in guiding drug development, while three-dimensional (3D) cell cultures have…

Trends in prevalence and predictors of anemia among school-aged children in Tanzania: analysis of 2019–2023 cross-sectional surveys using a multilevel logistic regression model

Anemia constitutes a major global public health challenge among school-aged children with documented impacts on psychomotor development, academic ach…

The National Allergy Centre of Excellence–Addressing Australia's Allergy Burden

Australia has one of the highest rates of food allergy, anaphylaxis hospital admissions and anaphylaxis fatalities worldwide. These trends and sustai…

Consideration of Child and Family Information in Clinical Decision Making

With persistent challenges in determining the 'right' therapy or support for autistic children, there is a growing need for clinicians to integrate t…

Relationship between serum clozapine to N-desmethyclozapine ratio and cognitive performance among people with treatment-resistant schizophrenia

We evaluated the relationship of serum clozapine and N-desmethyl clozapine and their ratio and cognition among people with treatment-resistant schizo…