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News & Events
Low Carbohydrate DietsCarbohydrate restriction is used by some individuals with type 1 diabetes to reduce glucose excursions after eating a meal.
News & Events
WA teenager with type 1 diabetes on a mission to become a pro-cyclistA wiry tall teenager, who was struggling somewhat with his blood glucose control, he turned up on his trusty bike, and we had something in common to talk about.
News & Events
Carol's story: losing a parent to RHDAfter being diagnosed with rheumatic heart disease at ten, Elizabeth had to leave country and her family for a large chunk of her childhood so she could be treated in Adelaide.
News & Events
Great minds come together at Wal-yan Scientific RetreatWal-yan Respiratory Research Centre team members and special guests travelled to Wadjemup (Rottnest) on 27 and 28 October to spend an intensive two days together learning about, and providing input into, the broad range of research projects underway within the Centre.
News & Events
Allied Health award for respiratory researcher Dr Pamela LairdCongratulations to respiratory health clinician-researcher Dr Pamela Laird, who has won Allied Health Researcher of the Year at the WA Excellence in Allied Health Awards.
Research
A newborn's perspective on immune responses to foodIn this review, we will highlight infants' immune responses to food, emphasizing the unique aspects of early-life immunity and the critical role of breast milk as a food dedicated to infants. Infants are susceptible to inflammatory responses rather than immune tolerance at the mucosal and skin barriers, necessitating strategies to promote oral tolerance that consider this susceptibility.
Research
CP Movetime: A wearable sensor and user interface to reduce sedentary behaviours in non-ambulant children and youth with cerebral palsyCP Movetime aims to establish and test a technology-based application to improve health outcomes by monitoring device measured sedentary behaviours in non-ambulant children and youth with cerebral palsy.
Research
Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastomaMedulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine.
Research
Comparing Web-Based Mindfulness With Loving-Kindness and Compassion Training for Promoting Well-Being in Pregnancy: Protocol for a Three-Arm Pilot Randomized Controlled TrialPromoting psychological well-being and preventing distress among pregnant women is an important public health goal. In addition to adversely impacting the mother's health and well-being, psychological distress in pregnancy increases the risk of poor pregnancy outcomes, compromises infant socioemotional development and bonding, and heightens maternal and child vulnerability in the postpartum period. Mindfulness and compassion-based interventions show potential for prevention and early intervention for perinatal distress.
Research
Literacy and Numeracy Underachievement in Boys and Girls With ADHDChildren with ADHD are disadvantaged from an early age in key areas of learning, and this risk increased with reduction in gestational age at birth