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Research

Attenuation of maternal inflammatory responses during pregnancy to promote normal immune and behavioral outcomes in the offspring

This study will identify how the immune system contributes to neurodevelopmental outcomes and will investigate the use of an agent from traditional medicines.

Research

Centre for Advanced Cancer Genomics (CACG)

Current technologies to understand which genes are turned on or off only work on large amounts of biological samples. As a consequence all measurements we receive represent averages across multiple cell types present in the sample. The situation is comparable to studying the contents of a bowl of fr

Translational Genomics in Leukaemia

The Translational Genomics in Leukaemia team is focused on identifying the causes of leukaemia, with the goal of developing new targeted treatments to improve quality of care and long-term survival for all children with leukaemia.

Research

Adolescent type 1 diabetes cardio-renal Intervention trial

An international clinical trial looking at intervention with Angiotensin Converting Enzyme Inhibitors (ACEI), Statins, or a combination of both

Research

Intranasal Insulin Trial II

If successful, this vaccine could prevent type 1 diabetes and the need for daily insulin injections in people at risk.

Mitochondrial Medicine and Biology

Mitochondrial diseases are devastating disorders for which there are no cures or effective treatments. Our project will focus on the prevention of mitochondrial diseases and discovery of effective cures.

Research

Epidemiology of T2DM in childhood and associated disease complications

Investigating the incidence of childhood Type 2 Diabetes in the Western Australian community

Global Disease Modelling

The Global Disease Modelling group informs development and implementation of drugs, medical treatments and non-medical interventions to effectively tackle disease. They build mathematical models of diseases, designed to take into account the complex constellation of interactions between pathogens, humans, diseases, the environment and entire healthcare systems.

ORIGINS

The ORIGINS Team is studying early environments and parental physical health and genetics to uncover when and why non-communicable diseases (NCDs) develop.