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Study the innate immune function in ulcerative colitis patients who fail to respond to anti-tumor necrosis factor therapy

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Mechanisms-including aerobiological and epigenetic-that might help explain some of the noted positive health outcomes

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determining if regular consumption of egg protein from age 4 to 6 months reduces the risk of IgE mediated allergy in infants with genetic risk, without eczema.

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Over the past decade, a growing number of studies have linked urban green space and aspects of biodiversity with emotional wellbeing.

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We argue that the success of planetary health solutions is predicated on a more sophisticated understanding of the psychology of prevention and intervention at all scales

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This review covers basic aspects of histone modification and the role of posttranslational histone modifications in the development of allergic diseases

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Here, we explore the history of planetary health and describe its relevance to contemporary healthcare

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There is a growing need for early biomarkers that may predict the development of atopic dermatitis (AD). As alterations in skin barrier may be a primary event in disease pathogenesis, epithelial cell (EC) cytokines expression patterns may be a potential biomarker in early life to target allergy preventive strategies towards "at-risk" infants. The aim of this longitudinal investigation was to examine from birth over the course of infancy levels of the EC cytokines: thymic stromal lymphopoietin (TSLP), interleukin (IL)-33, IL-25, and IL-17 in infants at high-risk of AD due to maternal atopy.

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To our knowledge, this is the first study to show that the reported 25(OH)D concentration may be influenced by both age and assay type

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To show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy.