Recurrent acute otitis media (AOM), frequently caused by Streptococcus pneumoniae, is a major paediatric health problem.
Bacteria persist within biofilms on the middle ear mucosa of children with recurrent and chronic otitis media however the mechanisms by which these...
We conducted an open randomized controlled trial in Papua New Guinea to compare safety, immunogenicity and priming for memory of 7-valent PCV (PCV7)…
Acute rheumatic fever (ARF) is an important cause of heart disease in Indigenous people of northern and central Australia.
This study was the first to concurrently identify middle ear pathogens in both bacterial biofilm and intracellularly in the middle ear mucosa of chil…
We evaluated baseline data from the PApilloma TRIal against Cancer In young Adults (PATRICIA; NCT00122681) on the association between behavioral risk…
One explanation for the high burden of allergic and autoimmune diseases in industrialized countries is inappropriate immune development under modern.…
A bivalent, recombinant, factor H-binding protein (rLP2086) vaccine was developed to protect against invasive Neisseria meningitidis serogroup B (MnB…
Pneumococcal colonization of the nasopharynx is especially common in young children and is a pre-requisite for pneumococcal disease...
Despite an effective vaccine, measles remains a major health problem globally, particularly in developing countries. More than 30% of children show p…