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Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapyTopical application of tumors with the TLR7 agonist imiquimod is an effective adjunct treatment for a range of primary dermatological cancers.
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Airway narrowing assessed by anatomical optical coherence tomography in vitro: dynamic airway wall morphology and functionPrevious histological and imaging studies have shown the presence of variability in the degree of bronchoconstriction of airways sampled at different locations.
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Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cellsTumor cell death potentially engages with the immune system. However, the efficacy of anti-tumor chemotherapy may be limited by tumor-driven...
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Effects of simulated tidal and deep breathing on immature airway contraction to acetylcholine and nerve stimulationIn adults, respiratory movements, such as tidal and deep breaths, reduce airway smooth muscle force and cause bronchodilation.
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Sugar sweetened beverage consumption by Australian children: Implications for public health strategyHigh consumption of sugar sweetened beverages (SSBs) has been linked to unhealthy weight gain and nutrition related chronic disease.
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Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised childrenWe aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked.
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Intellectual disability: Population-based estimates of the proportion attributable to maternal alcohol use disorder during pregnancyThe aim of this study was to examine the association between maternal alcohol use disorder and intellectual disability in children.
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The relationship between MECP2 mutation type and health status and service use trajectories over time in a Rett syndrome populationThis study aimed to investigate the trajectories over time of health status and health service use in Rett syndrome by mutation...
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Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specificChronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear
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Modulation of the immune system by UV radiation: More than just the effects of vitamin D?Humans obtain most of their vitamin D through the exposure of skin to sunlight