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Research
Developing and characterising juvenile models of aggressive paediatric brain cancers for the evaluation of novel immunotherapiesNick Raelene Terrance Gottardo Endersby Johns MBChB FRACP PhD BSc (Hons) PhD Head of Paediatric and Adolescent Oncology and Haematology, Perth
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Understanding the true burden of paediatric respiratory syncytial virus (RSV) in order to optimise prevention programsHannah Moore OAM BSc (Hons) GradDipClinEpi PhD Head, Infectious Diseases Research 08 6319 1427 Hannah.moore@thekids.org.au Head, Infectious Diseases
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The pathogen specific burden of hospitalisation for enteric and blood stream infection in children and young people in Western AustraliaHannah Tom Moore Snelling OAM BSc (Hons) GradDipClinEpi PhD BMBS DTMH GDipClinEpid PhD FRACP Head, Infectious Diseases Research Head, Infectious
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Educational Outcomes of Children in Contact with the Child Protection System: A Longitudinal Population StudyMelissa Fiona Helen O'Donnell Stanley Leonard BPsych (Hons), MPsych, GradDip Ed, PhD FAA FASSA MSc MD FFPHM FAFPHM FRACP FRANZCOG HonDSc HonDUniv
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Acceptability of sonicated versus unsonicated reconstituted (powdered) benzathine penicillin G for rheumatic fever prophylaxisPowdered benzathine penicillin G (BPG) crystals vary widely in size and shape and are larger and less uniform than crystals found in pre-mixed suspensions of BPG like Bicillin ® L-A.
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Defining target penicillin concentrations for subsequent studies of a reformulated long-acting benzathine penicillin prototypeAims: To determine the minimum inhibitory concentrations of penicillin G against a representative collection of Strep A strains; and to evaluate the impact of penicillin G concentration and size of bacterial inoculum on the prophylactic effect for Strep A strains
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Molecular Detection of Scabies by PCR Using a Next Generation Sequencing (NGS) ApproachIn recent years, the interest in molecular diagnostic methods for the detection of many pathogens has grown substantially.
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Pharmacokinetics of intramuscular versus subcutaneous administration of Benzathine Penicillin GBenzathine penicillin G (BPG) has been in use since the 1950s for treatment of skin infections, bacterial pharyngitis, syphilis and prevention of recurrent episodes of acute rheumatic fever (ARF)
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The NZ BPG Pharmacokinetics StudyThis work will be undertaken in collaboration with The Kids Research Institute Australia and Australian based research teams to better understand how Penicillin works in Māori and Pacific children/teens who receive monthly BPG injections.
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Working Towards a Better Understanding of ARFGoal: Characterize the pattern of contemporary and endemic ARF and develop a biological signature to improve sensitivity and specificity of ARF diagnosis.