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Difficult but doable: Health professional perspectives of assessing clinical deterioration in children with dark-coloured skin

Observable signs of clinical deterioration may present differently in children with dark-coloured skin, leading to potential missed or delayed recogn…

The Promoting Resilience in Stress Management for Parents (PRISM-P) Intervention: A Pilot Randomised Controlled Trial in Parents of Young Children With Type 1 Diabetes

Parents of young children with type 1 diabetes (T1D) are at risk of experiencing elevated stress due to their responsibilities as caregivers. Despite…

Insights from a trial of narrowband UVB for early multiple sclerosis

There is a greater prevalence of multiple sclerosis (MS), a neurological autoimmune condition, in populations living further from the equator, hypoth…

BEAT-BK: An Adaptive, Randomized Controlled Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Kidney-pancreas Transplantation Recipients (BEAT-BK) Study Protocol

BK polyomavirus (BKPyV) is a common opportunistic infection in kidney transplant recipients, typically reactivating in the context of immunosuppressi…

Acute Rheumatic Fever Diagnostic Network (ARC Network) clinical recruitment protocol

Rheumatic heart disease, a major cause of morbidity and mortality in low- and middle-income countries, results from acute rheumatic fever (ARF), for…

Performance of published scoring tools for predicting the risk of perioperative respiratory adverse events in children - An evaluation in a large paediatric cohort

Perioperative respiratory adverse events (PRAE) are a main cause of morbidity and mortality in paediatric anaesthesia. Clinicians need to be able to…

Challenges and insights in self-swab surveillance for asymptomatic Streptococcus pyogenes carriage

Asymptomatic carriage of Streptococcus pyogenes (Strep A) may contribute to transmission, yet its role remains poorly understood and evidence on opti…

Prospective effects of positive resilience resources during young adulthood: Predicting daily stress responses three years later amidst a changing world

With young adults' rates of mental health problems alarmingly high, understanding resilience characteristics that help young people adapt, adjust, an…

Psychosocial aspects of early detection in type 1 diabetes: Language matters, decision making and support needs

The potential implementation of early type 1 diabetes (T1D) detection pathways, encompassing autoantibody screening and longitudinal monitoring, rais…

The impact of social determinants of health on paediatric perioperative adverse events - a narrative review

The social determinants of health, as described by the World Health Organisation (WHO), are 'the non-medical factors' that influence health outcomes.…