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The ORIGINS Project Biobank: A Collaborative Bio Resource for Investigating the Developmental Origins of Health and DiseaseEarly onset Non-Communicable Diseases (NCDs), including obesity, allergies, and mental ill-health in childhood, present a serious and increasing threat to lifelong health and longevity. The ORIGINS Project (ORIGINS) addresses the urgent need for multidisciplinary efforts to understand the detrimental multisystem impacts of modern environments using well-curated large-scale longitudinal biological sample collections.
Research
Beyond Plants: The Ultra-Processing of Global Diets Is Harming the Health of People, Places, and PlanetGlobal food systems are a central issue for personal and planetary health in the Anthropocene. One aspect of major concern is the dramatic global spread of ultra-processed convenience foods in the last 75 years, which is linked with the rising human burden of disease and growing sustainability and environmental health challenges.
Research
PKC activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensityA significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells, associated with reduced ability to transition from a neonatal Th2 to a mature Th1 cytokine bias, leading to a higher risk of developing allergic sensitisation, compared to neonates whose T cells have 'normal' PKCζ levels. However, the importance of PKCζ signalling in regulating their differentiation from a Th2 to a Th1 cytokine phenotype propensity remains undefined.
Research
The feasibility of a digital health approach to facilitate remote dental screening among preschool children during COVID-19 and social restrictionsTele-dentistry can be useful to facilitate screening of children, especially those living in rural and remote communities, and during the COVID-19 pandemic. This study evaluated the feasibility of tele-dental screening for the identification of early childhood caries (ECC) in preschoolers using an app operated by their parents with remote review by oral-health therapists.
News & Events
Tackling allergy prevention in early lifeThe Childhood Allergy and Immunology Research Team at The Kids Research Institute Australia are currently conducting four studies, through ORIGINS, investigating nutritional strategies in the diets of mothers and babies and how these may reduce the development of allergies.
News & Events
Child health and obesity the focus of international built environment studyResearch data from more than one million Australian and Welsh children will be examined to help better understand how the built environment affects child health and obesity, as part of an international research project to be co-led by The Kids Research Institute Australia.
News & Events
Shopping For Data to Drive DiscoveriesWhat if researchers could shop for different data to help uncover how, when and why chronic conditions such as asthma, obesity, allergies and poor mental health develop?
News & Events
ORIGINS Ch7 News StoryORIGINS featured on Channel 7 News recently with two family stories of how ORIGINS changed their lives.
News & Events
Tips for protecting your baby in the summer heatPaediatrician Dr Lana Bell shares her top tips for keeping your baby or toddler cool, well-hydrated and protected as the temperature soars.
News & Events
Prospective Student EveningStudents met ORIGINS team at the recent Prospective Student Evening at Telethon Kids Institute.