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Identifying pediatric lung disease: A comparison of forced oscillation technique outcomes

Identifying pediatric lung disease: A comparison of forced oscillation technique outcomes Abstract Rationale Increasing evidence suggests the forced

The genomic evolutionary dynamics and global circulation patterns of respiratory syncytial virus

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection in young children and the second leading cause of infant death worldwide. While global circulation has been extensively studied for respiratory viruses such as seasonal influenza, and more recently also in great detail for SARS-CoV-2, a lack of global multi-annual sampling of complete RSV genomes limits our understanding of RSV molecular epidemiology.

How Families Manage the Complex Medical Needs of Their Children with MECP2 Duplication Syndrome

MECP2 duplication syndrome (MDS) is a rare, X-linked, neurodevelopmental disorder resulting from the duplication of the methyl-CpG-binding protein 2 (MECP2) gene. The clinical features of MDS include severe intellectual disability, global developmental delay, seizures, recurrent respiratory infections, and gastrointestinal problems. The aim of this qualitative study was to explore how the parents of children with MDS manage their child's seizures, recurrent respiratory infections, and gastrointestinal symptoms, and the impact on them as parents.

An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solution

Typhoid fever is a major global health problem, the control of which is hindered by lack of a suitable animal model in which to study Salmonella Typhi...

Impact of health-oriented marketing claims on young adults’ alcohol product perceptions, hypothetical consumption, and beliefs: a randomized experiment

Health-oriented marketing claims commonly and increasingly feature on alcohol products and target younger consumers. This study aimed to test effects of such claims on young adults' alcohol product perceptions and intended consumption.

Serotonin and aggressive behaviour in children and adolescents: a systematic review

Findings were mixed, with support both for negative and for positive associations of central nervous 5-HT function with aggression in children and adolescents

The impact of Influenza infection during early life on immune development

This study will investigate the why disease is worse in infants and how early life viral infection impacts the developing immune system.

Survival of children and adolescents with intellectual disability following gastrostomy insertion

Whilst gastrostomy insertion was associated with lower survival rates than children without gastrostomy, survival improved with time

Association between pregnant women's experience of stress and partners’ fly-in-fly-out work

There is some evidence that the pregnant partners of fly-in-fly-out workers perceive their lives to be more stressful

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability.

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability. Rationale: No studies