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New meningococcal strains bring increased risk in WAA new study has confirmed the changing pattern of meningococcal disease in Western Australia.
Research
A diagnostic test for acute rheumatic fever (pilot study)Currently there are no diagnostic tests for ARF, and no treatments targeting immune responses to improve disease outcomes.
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Burden of rheumatic heart disease (RHD) and impact of prevention strategies: comprehensive evidence to drive the RHD EndgameJonathan Judy Rosemary Carapetis AM Katzenellenbogen Wyber AM MBBS FRACP FAFPHM PhD FAHMS BSc (Occ Ther) BSc Hons (Epidemiol) MSc PhD MBChB MPH
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Controlled Human Infection for Penicillin Against Streptococcus pyogenes – a double blinded randomised trail (The CHIPS trial)In Australia, RHD-related death and disability is the leading driver of cardiovascular inequality between Indigenous and non-Indigenous Australians.
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In Vitro primary human airway epithelial whole exhaust exposureThe method outlined in this article is a customization of the whole exhaust exposure method generated by Mullins et al. (2016) using reprogrammed primary human airway epithelial cells as described by Martinovich et al. (2017). It has been used successfully to generate recently published data (Landwehr et al. 2021). The goal was to generate an exhaust exposure model where exhaust is collected from a modern engine, real-world exhaust concentrations are used and relevant tissues exposed to assess the effects of multiple biodiesel exposures.
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Clinical development strategy for a candidate group A streptococcal vaccineThis review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin
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Exacerbation of chronic cigarette-smoke induced lung disease by rhinovirus in miceA significant proportion of chronic obstructive pulmonary disease exacerbations are strongly associated with rhinovirus infection (HRV). In this study, we combined long-term cigarette smoke exposure with HRV infection in a mouse model.
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Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart DiseaseRheumatic heart disease affects more than 40.5 million people worldwide and results in 306,000 deaths annually. Echocardiographic screening detects rheumatic heart disease at an early, latent stage. Whether secondary antibiotic prophylaxis is effective in preventing progression of latent rheumatic heart disease is unknown.
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The global epidemiology of impetigo: A systematic review of the population prevalence of impetigo and pyodermaWe conducted a comprehensive, systematic review of the global childhood population prevalence of impetigo and the broader condition pyoderma.
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Biodiesel exhaust: The need for a systematic approach to health effects researchBiodiesel is a generic term for fuel that can be made from virtually any plant or animal oil via transesterification of triglycerides with an alcohol...