Sex-related differences in bronchial hyperresponsiveness (BHR) have been reported in adolescents, but the mechanisms remain obscure.
Chronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear
The airway epithelium forms a highly regulated physical barrier that normally prevents invasion of inhaled pathogens and allergens from the airway lu…
The introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficult…
Asthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incura…
Atopic asthma is the most common form of asthma, particularly during childhood, and in many cases it persists into adult life.
Vitamin D has been linked in some studies with atopy- and asthma-associated phenotypes in children with established disease,but its role in disease i…
Characterization of the complete IgE binding spectrum of cat allergens is important for the development of improved diagnosis and effective immunothe…
An improved understanding of the roles of protein kinases in intracellular signalling and disease progression has driven significant advances in prot…
Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.