The aim of this study was to assess if MMP activation positively correlates with neutrophil elastase activity, disease severity and bronchiectasis in…
To investigate changes in trapped air volume and distribution over time and compare computed tomography (CT) with pulmonary function tests for determ…
Chest computed tomography (CT) is the gold standard for demonstrating cystic fibrosis (CF) airway disease. However, there are no standardized outcome…
Airway inflammation and infection are present from early in life, often before children are symptomatic.
Biomarkers in cystic fibrosis are used for the measurement of cystic fibrosis transmembrane regulator function in order to diagnose cystic fibrosis,.…
No evidence to demonstrate relationships with symptoms and viruses, prolonged symptoms, prolonged shedding or patterns of virus infections in CF
Determinants of culture success through retrospective analysis of a program of routinely brushing children with Cystic Fibrosis airway disease
We hypothesized that allergic inflammation decreases the level of circulating 25(OH)D and tested this using a mice model of house dust mite (HDM) ind…
We hypothesized that the presence of these markers of cystic fibrosis lung disease in the first 2 years of life would be associated with reduced lung…
Despite our current treatment, many cystic fibrosis (CF) patients still show progressive bronchiectasis and small airways disease.