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Development of an International Database for a Rare Genetic Disorder: The MECP2 Duplication Database (MDBase)The natural history of MECP2 duplication syndrome (MDS), a rare X-linked neurodevelopmental disorder with an estimated birth prevalence of 1/150,000 live births, is poorly understood due to a lack of clinical data collected for research. Such information is critical to the understanding of disease progression, therapeutic endpoints and outcome measures for clinical trials, as well as the development of therapies and orphan products.
Research
The 'Can't Intubate Can't Oxygenate' scenario in pediatric anesthesia: A comparison of the Melker cricothyroidotomy kit with a scalpel bougie techniqueWhile the majority of pediatric intubations are uncomplicated, the 'Can't intubate, Can't Oxygenate' scenario (CICO) does occur.
Research
The effect of 100% oxygen on tidal breathing parameters in preschool childrenThis study aimed to determine whether breathing 100% oxygen altered tidal breathing parameters in healthy young children and young children with CF.
Research
The safety and feasibility of the inhaled mannitol challenge test in young childrenMannitol challenge tests are used clinically to diagnose asthma and, in particular, exercise-induced broncoconstriction (EIB) in adults and children above 6...
Research
Characterization of maximal respiratory pressures in healthy childrenMeasurements of maximal voluntary inspiratory (Pi max) and expiratory (Pe max) pressures are used in the management of respiratory muscle disease...
News & Events
Lung problems continue into childhood for premmie babiesNew research from Perth’s The Kids Research Institute Australia shows that babies born premature continue to have lung problems well into childhood.
Research
Infection, inflammation,and lung function decline in infants with cystic fibrosisBetter understanding of evolution of lung function in infants with cystic fibrosis...
Research
Reference values for spirometry: The way forward for our patientsFew clinical respiratory laboratories have assessed the impact of changing reference equations on the interpretation of spirometric outcomes.
Research
Lung volume and ventilation inhomogeneity in preterm infants at 15-18 months corrected ageTo assess whether lung volume and ventilation inhomogeneity in preterm infants at 15-18 months corrected age
News & Events
The Kids Research Institute Australia welcomes tough new measures to save kids from vapingThe Kids Research Institute Australia strongly supports the Federal Government’s announcement today to introduce a suite of reforms aimed at banning non-prescription vaping products in Australia.