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Research
Lung function in African infants in the Drakenstein child health study impact of lower respiratory tract illnessEarly life lower respiratory tract illness impairs lung function at 1 year, independent of baseline lung function
Research
Key paediatric messages from the 2016 european respiratory society international congressIn this article, the Group Chairs of the Paediatric Assembly of the European Respiratory Society (ERS) highlight some of the most interesting abstracts presented at the 2016 ERS International Congress, which was held in London.
The Foundations of Lung Disease Team investigates lung growth and development through infancy, childhood, adolescence and early adulthood, in health and in chronic lung disease, and the impact of preterm birth on lung health outcomes.
News & Events
The Kids Research Institute Australia welcomes tough new measures to save kids from vapingThe Kids Research Institute Australia strongly supports the Federal Government’s announcement today to introduce a suite of reforms aimed at banning non-prescription vaping products in Australia.
News & Events
Lung problems continue into childhood for premmie babiesNew research from Perth’s The Kids Research Institute Australia shows that babies born premature continue to have lung problems well into childhood.
Research
Biomarkers to define the treatment end-point for pulmonary exacerbations in cystic fibrosisAdvances in our understanding of early cystic fibrosis lung disease led by the Australian Early Surveillance Team for Cystic Fibrosis (AREST CF) have also indicated the potential utility of a number of biomarkers for monitoring disease severity.
Research
Elevated leukotriene B4 and 8-isoprostane in exhaled breath condensate from preterm-born infantsInflammation and oxidative stress play a key role in the development of bronchopulmonary dysplasia (BPD), possibly contributing to persistent respiratory morbidity after preterm birth. We aimed to assess if inflammatory markers were elevated in exhaled breath condensate (EBC) of infants born very prematurely (< 32 weeks gestation) at 12-16 corrected months of age, and if increased levels were associated with BPD diagnosis and respiratory morbidity.
Research
Performance Accuracy of Wrist-Worn Oximetry and Its Automated Output Parameters for Screening Obstructive Sleep Apnea in ChildrenObstructive sleep apnea (OSA) increases the risk of perioperative adverse events in children. While polysomnography remains the reference standard for OSA diagnosis, oximetry is a valuable screening tool. The traditional practice is the manual analysis of desaturation clusters derived from a tabletop device using the McGill oximetry score. However, automated analysis of wearable oximetry data can be an alternative. This study investigated the accuracy of wrist-worn oximetry with automated analysis as a preoperative OSA screening tool.
Research
Characterization of maximal respiratory pressures in healthy childrenMeasurements of maximal voluntary inspiratory (Pi max) and expiratory (Pe max) pressures are used in the management of respiratory muscle disease...
Research
The safety and feasibility of the inhaled mannitol challenge test in young childrenMannitol challenge tests are used clinically to diagnose asthma and, in particular, exercise-induced broncoconstriction (EIB) in adults and children above 6...