The aim of this study was to assess the relationship between dust levels and health in Indigenous children in Western Australia
Protease elastase exocytosis by airway neutrophils occurs in all cystic fibrosis children, and its cellular measure correlates with early lung damage
This chapter will discuss the structure of the airway highlighting the now broad number of cell types that comprise it
In this Review, we consolidate the latest updates in the development of primary epithelial cellular model systems relevant for cystic fibrosis
This study demonstrates the feasibility of utilizing pre-clinical in vitro culture models to screen therapeutic candidates
A better understanding of the innate immune responses by CF airway epithelial cells is needed to identify why viral infections are more severe in CF
Our data associates IL-1α with early structural lung damage in CF and suggests this pathway as a novel anti-inflammatory target
A lung function study carried out by Dr Shannon Simpson provided the most comprehensive follow-up of very pre-term children of any study so far carri…
Here we review the current knowledge of key molecular pathways that are dysregulated during persistent goblet cell differentiation
This study demonstrates novel intrinsic differences in tight junctions gene and protein expression between airway epithelial cells of children with a…