Upper and lower airways are conserved in their transcriptional composition, and variations associated with disease are present in both nasal and trac…
Chronic airway injury and dysregulated repair programs are evident in airway epithelium obtained from patients with bronchiolitis obliterans syndrome
In this translational review, the mechanisms, roles, and impact of epithelial-mesenchymal transition in chronic lung diseases are discussed
This study found rhinovirus infection drives necrotic cell death in cystic fibrosis airway epithelial cells
Here we examine the latest findings of neutrophils in pediatric CF lung disease and proposed mechanisms of their pathogenicity
We demonstrate that NOTCH3 is a regulator of MUC5AC production
Our data illustrate that rhinovirus infection is capable of infecting upper and lower airway epithelial cells, driving cell death and inflammation
Several lipid biomarkers of early cystic fibrosis lung disease were identified, which point toward potential disease monitoring and therapeutic appro…
Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls an…
This review examines the consequences of preterm birth on the airway epithelium and explores the clinical relevance of currently available models