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Factors influencing the assessment of lung function in mice with influenza-induced lung disease

The constant-phase model (CPM) is commonly fit to respiratory system input impedance (Z rs) to estimate lung mechanics.

The mechanism of deep inspiration-induced bronchoprotection: Evidence from a mouse model

In healthy individuals, deep inspirations (DIs) taken prior to a bronchial challenge reduce the bronchoconstrictor response, which is termed...

Acute diesel exhaust particle exposure increases viral titre and inflammation associated with existing influenza

Exposure to diesel exhaust particles (DEP) is thought to exacerbate many pre-existing respiratory diseases.

Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of risk

A hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial...

Sensitizing and Th2 Adjuvant Activity of Cysteine Protease Allergens

Here, we report on a model that does not use Th2-skewing adjuvants and yet achieves sensitization solely via the nasal mucosa.

Sexual dimorphism in lung function responses to acute influenza A infection

Males are generally more susceptible to respiratory infections; however, there are few data on the physiological responses to such infections in male…

In utero cigarette smoke exposure impairs somatic and lung growth in BALB/c mice

The aim of this study was to assess whether in utero tobacco smoke exposure alone affects early-life lung growth and development. Pregnant BALB/c mic…

Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control

The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation.

Self-citation in American Physiological Society Journals

This study investigates the incidence of self-citation (authors citing their own work) for scholarly articles in ten journals published by the Americ…

Emerging issues in the Pacific Basin

This review provides a snapshot of some key environmental health issues that will provide ongoing challenges for the Pacific Basin region in the comi…