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Research

Rationale for use for monoclonal antibody and anti-cytokine therapy for multisystem inflammatory syndrome in children: A systematic review

Objective: To review systematically the rationale for choice and use of monoclonal antibody and anti-cytokine therapy in multisystem inflammatory syndrome in children.

Research

Protocol for the Australian Type 1 Diabetes National Screening Pilot: Assessing the feasibility and acceptability of three general population screening models in children

One third of Australian children diagnosed with type 1 diabetes present with life-threatening diabetic ketoacidosis (DKA) at diagnosis. Screening for early-stage, presymptomatic type 1 diabetes, with ongoing follow-up, can substantially reduce this risk (<5% risk). Several screening models are being trialled internationally, without consensus on the optimal approach. This pilot study aims to assess three models for a routine, population-wide screening programme in Australia.

Research

Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways

nfants with frequent viral and bacterial respiratory infections exhibit compromised immunity to routine immunizations. They are also more likely to develop chronic respiratory diseases in later childhood. This study investigated the feasibility of epigenetic profiling to reveal endotype-specific molecular pathways with potential for early identification and immuno-modulation. 

Research

Towards Harmonized Adolescent Health Measurement: Assessing Alignment Between Current Recommendations and the Global Action for Measurement of Adolescent Health–Recommended Indicators

This study identified alignment of indicators across different initiatives and data collection instruments as a foundation for future harmonization of adolescent health measurement.

News & Events

Groundbreaking TB researcher named AAMRI Rising Star

Dr Kefyalew Alene, who heads the Geospatial and Tuberculosis team at The Kids and is a senior research fellow within the Curtin School of Population Health, has used cutting edge technology to transform the way TB transmission is predicted, understood and managed globally.

News & Events

Research breakthrough gives hope to children with rare and undiagnosed diseases

A complex five-year experiment which cracked the code of a genetic mystery has paved the way for faster and more accurate diagnoses of the most rare and unknown diseases affecting children.

News & Events

Pitch perfect projects powered by philanthropy

Earlier this week ten emerging researchers took to the stage to pitch their projects to a room full of excited and engaged philanthropists who share our vision of happy, healthy kids.

News & Events

Flying the flag for WA research thanks to Business Events Aspire Awards

Dr Matthew ‘Tepi’ Mclaughlin is the 2022 The Kids Research Institute Australia Aspire Award winner - coordinated by Western Australia’s peak body for business events, Business Events Perth.

News & Events

The Impact of Poverty - interview with Steve Zubrick

Growing up poor is about more than just the size of your bank account. Read the new CoLab Impact of Poverty Evidence Report.

News & Events

$1.2million in funding secured for two innovative projects

The Kids researchers are collaborating on two major projects that today received $1.2million in funding from MTPConnect.