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Research
Defective respiratory tract immune surveillance in asthma : A primary causal factor in disease onset and progressionThe relative importance of respiratory viral infections vs inhalant allergy in asthma pathogenesis is the subject of ongoing debate.
Research
Energy drink consumption is associated with anxiety in australian young adult malesEnergy drinks are predominantly targeted to young adult consumers; however, there has been limited research into their effects on psychological functioning...
Research
Unpacking the complex nature of the autism epidemicThe etiology of autism spectrum disorders is unknown but there are claims of increasing prevalence in many countries.
News & Events
Philanthropy powering our people at PitchFest!For the third year running, ten emerging researchers took to the stage to pitch their innovative research projects at our annual Illuminate PitchFest event, inspiring a room full of donors of their vision and commitment to drive improved health outcomes for kids.
News & Events
ORIGINS celebrates significant funding from the Stan Perron Charitable Foundation in 2025A substantial funding boost from the Stan Perron Charitable Foundation will help to further extend one of Australia’s biggest longitudinal child health research studies centred around families from the Joondalup and Wanneroo communities.
Research
Early Irritability as a Transdiagnostic Neurodevelopmental Vulnerability to Later Mental Health ProblemsIrritability is a common trait seen in children. While expressions of irritability are part of normal development, servere irritability is a known indicator of child and adolescent mental health problems.
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Normative data for multiple breath washout outcomes in school-aged Caucasian childrenThe multiple breath nitrogen washout (N2MBW) technique is increasingly used to assess the degree of ventilation inhomogeneity in school-aged children with lung disease. However, reference values for healthy children are currently not available.
Research
Continuity of temperament subgroup classifications from infancy to toddlerhood in the context of early autism traitsOur previous cross-sectional investigation (Chetcuti et al., 2020) showed that infants with autism traits could be divided into distinct subgroups based on temperament. This longitudinal study builds on this existing work by exploring the continuity of temperament subgroup classifications and their associations with behavioral/clinical phenotypic features from infancy to toddlerhood.
Research
Change in health outcomes for First Nations children with chronic wet cough: rationale and study protocol for a multi-centre implementation science studyIn children, chronic wet cough may be a sign of underlying lung disease, including protracted bacterial bronchitis (PBB) and bronchiectasis. Chronic (> 4 weeks in duration) wet cough (without indicators pointing to alternative causes) that responds to antibiotic treatment is diagnostic of PBB. Timely recognition and management of PBB can prevent disease progression to irreversible bronchiectasis with lifelong consequences. However, detection and management require timely health-seeking by carers and effective management by clinicians.
Research
Psychological Flow Scale (PFS): Development and Preliminary Validation of a New Flow Instrument that Measures the Core Experience of Flow to Reflect Recent Conceptual AdvancementsIn this study, we sought to develop—and provide preliminary validity evidence for scores derived from—a new Psychological Flow Scale (PFS). We propose a parsimonious model of three core dimensions of flow, reflecting the findings from a recent scoping review that synthesised flow research across scientific disciplines.