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Rehabilitation service provision and outcomes for children with stroke in Victoria and Western Australia in the pre-implementation era of clinical practice guidelines

This study described the rehabilitation services accessed by children with stroke following acute admission to two Australian paediatric tertiary hospitals prior to the implementation of clinical practice guidelines. It also evaluated quality-of-care indicators for inpatient rehabilitation within these two settings.

Epigenetic modifications: Mechanisms of disease and biomarkers of food allergy

The rise in IgE-mediated food allergy in recent times is the likely result of gene-environment interactions mediated via epigenetic pathways.

General Movement Optimality Score-Revised (GMOS-R) with General Population-Based Percentile Ranks

To describe writhing General Movements Assessment (GMA) classification and General Movement Optimality Score-Revised (GMOS-R) profiles in the general population; to explore relationships between GMOS-R scores and GMA classification, age of assessment and infant socio-demographic factors; and to establish the inter-rater reproducibility of writhing age GMA classification and GMOS-R.

Factors Associated with Respiratory Illness in Children and Young Adults with Cerebral Palsy

Oromotor dysfunction is strongly associated with respiratory illness in patients with cerebral palsy

Symbiotic symphony: Understanding host-microbiota dialogues in a spatial context

Modern precision sequencing techniques have established humans as a holobiont that live in symbiosis with the microbiome. Microbes play an active role throughout the life of a human ranging from metabolism and immunity to disease tolerance. Hence, it is of utmost significance to study the eukaryotic host in conjunction with the microbial antigens to obtain a complete picture of the host-microbiome crosstalk. 

Prevalence of symptoms associated with respiratory illness in children and young people with cerebral palsy

This letter to the editor discusses the prevalence of symptoms associated with respiratory illness in children & young people with cerebral palsy.

A great way to bring up health behaviour topics at playgroup: a qualitative evaluation of the Healthy Conversations @ Playgroup program

The early years is a critical stage to establish optimal nutrition and movement behaviours. Community playgroups are a relaxed environment for parents with a focus on social connection and supporting parents in their role as 'First Teachers'. Playgroups are therefore an opportunistic setting to promote health behaviours in the early years.

Improving delivery of secondary prophylaxis for rheumatic heart disease in remote Indigenous communities

This trial aims to improve uptake of secondary prophylaxis among Aboriginal people with ARF/RHD to reduce progression or worsening of RHD.

Evaluation of the Strong Start Pilot Program

Yasmin Harman-Smith BA, BHlthSc(Hons), PhD Head, Early Years Systems Evidence; Head, Tenders Support Unit Yasmin.harman-smith@thekids.org.au Head,

Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms

Differences in regional GMV are discernible at an early stage of UHR and may be specific to individuals who have APS and psychopathology at follow-up

Psychological wellbeing outcomes across genders in childhood and adolescence aged 8–18 years: a population-level perspective

This study aimed to examine the difference in levels of psychological wellbeing outcomes of binary and non-binary transgender and cisgender students aged 8–18 years in South Australia using population-level data.

Screening for rheumatic heart disease: Quality and agreement of focused cardiac ultrasound by briefly trained health workers

After brief training, health workers with no prior experience in echocardiography can obtain adequate quality images and make a reliable assessment

Supporting Parents as their Child’s First Teacher: Aboriginal Parents’ Perceptions of KindiLink

This paper reports on Aboriginal parents’ perceptions about their involvement in a Western Australian pilot initiative called KindiLink. The program seeks to support parents as their child’s first teacher and thereby enhance Aboriginal children’s early-years development, while strengthening relationships between families and schools. A constructivist paradigm was used to inform the methodology which placed Aboriginal voices at the centre of the research.

Age at surgery and outcomes of an undescended testis

We investigated the prevalence of UDT and examined rates of surgery and age at surgery in an Australian population.

Perceptions of Stepfathers’ Obligations to Financially Support Stepchildren

This study highlights the heterogeneity and complexity of attitudes around this issue and associated social policies

Machine Learning-Based DNA Methylation Score for Fetal Exposure to Maternal Smoking

Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which therefore hold the potential to be used as a biomarker of this early life exposure. With declining costs for measuring DNA methylation, we aimed to develop a DNA methylation score that can be used on adolescent DNA methylation data and thereby generate a score for in utero cigarette smoke exposure.

Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease

Regular fat and reduced fat dairy products show similar associations with markers of adolescent cardiometabolic health

Intakes of both regular fat and reduced fat dairy products were associated with similar cardiometabolic associations in adolescents