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A screening tool to identify risk for bronchiectasis progression in children with cystic fibrosis

The marked heterogeneity in cystic fibrosis (CF) disease complicates the selection of those most likely to benefit from existing or emergent treatments. We aimed to predict the progression of bronchiectasis in preschool children with CF.

Citation:
Caudri D, Turkovic L, de Klerk NH, Rosenow T, Murray CP, Steyerberg EW, …… Stick SM, Breuer O. A screening tool to identify risk for bronchiectasis progression in children with cystic fibrosis. Pediatric Pulmonology. 2022;57(1):122-131.

Keywords:
Air trapping; bronchiectasis; lower respiratory infections; lower respiratory neutrophilic inflammation; pancreatic insufficiency; respiratory exacerbations

Abstract:
The marked heterogeneity in cystic fibrosis (CF) disease complicates the selection of those most likely to benefit from existing or emergent treatments. We aimed to predict the progression of bronchiectasis in preschool children with CF.