PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum
Large-scale molecular profiling studies in recent years have shown that central nervous system (CNS) tumors display a much greater heterogeneity in terms of molecularly distinct entities, cellular origins and genetic drivers than anticipated from histological assessment.
Keywords:
Brain tumor; ewsr1; Gene fusion; mn1; Neuroepithelial; Neurooncology;
patz1; Pediatric
Abstract:
Large-scale molecular profiling studies in recent years have shown that central nervous system (CNS) tumors display a much greater heterogeneity in terms of molecularly distinct entities, cellular origins and genetic drivers than anticipated from histological assessment.