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Directing the future breakthroughs in immunotherapy: The importance of a holistic approach to the tumour microenvironment

Immunotherapy has revolutionised the treatment of cancers by exploiting the immune system to eliminate tumour cells. Despite the impressive response in a proportion of patients, clinical benefit has been limited thus far.

Citation:
Newnes HV, Armitage JD, Audsley KM, Bosco A, Waithman J. Directing the future breakthroughs in immunotherapy: The importance of a holistic approach to the tumour microenvironment. Cancers. 2021;13(23).

Keywords:
Immunotherapy; Multi‐omics; Personalised therapy; Tumour microenvironment

Abstract:
Immunotherapy has revolutionised the treatment of cancers by exploiting the immune system to eliminate tumour cells. Despite the impressive response in a proportion of patients, clinical benefit has been limited thus far.