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Infectious Diseases Epidemiology

Our team’s vision is to reduce the burden of infectious diseases in children and their families through comprehensive approaches to understanding the burden of disease, developing and optimising diagnosis and treatment strategies and evaluating and informing current and future prevention programs.

Our group has a particular interest in acute lower respiratory infections, commonly known as chest infections.

These conditions include bronchiolitis and pneumonia and occurs secondary to viral and bacterial infections including viral pathogens respiratory syncytial virus (RSV), influenza, human metapneumovirus and parainfluenza virus and bacterial pathogens including Streptococcus pneumoniae and Bordetella pertussis. Chest infections are a major cause of childhood morbidity with some population subgroups experiencing higher rates of severe disease including Aboriginal and/or Torres Strait Islander children, those with co-morbidities and those from a lower socio-economic background.

The work of the Infectious Disease Epidemiology team centres around three key themes:

  • Burden of Disease – understanding pathogen-specific burden of disease, temporal and seasonal trends in disease and perinatal risk factors to disease in population groups using a range of data sources.
  • Prevention and Policy – evaluating current prevention policy, such as vaccination policy at local and population levels, incorporating assessment of vaccine coverage, cost effectiveness and overall program performance in reducing the incidence of disease. We also use data to advocate for new immunisation programs, including RSV.
  • Diagnosis and Treatment - developing ways to improve surveillance of and the diagnosis and treatment of severe respiratory infections in children through prospective cohort studies, clinical trials and use of administrative health data.

Our team employs an array of methodologies including epidemiological analyses of large-scale population-based linked administrative health data; statistical and mathematical modelling; undertaking prospective cohort studies and clinical trials; and conducting social research.

Team leader

Professor Hannah Moore
Professor Hannah Moore

OAM BSc (Hons) GradDipClinEpi PhD

Head, Infectious Diseases Research

Professor  Christopher Blyth
Professor Christopher Blyth

MBBS (Hons) DCH FRACP FRCPA PhD

Centre Head, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases Epidemiology, Wesfarmers Centre of Vaccines and Infectious Diseases, Honorary and NHMRC Emerging Leadership Fellow

Team members (19)

Anita Williams
Anita Williams

MInfecDis MPhil(App Epi)

Research Officer, Infectious Diseases Epidemiology

Belaynew Taye
Belaynew Taye

MD, MPH, PhD

Research Officer, Infectious Disease Epidemiology

Carla Puca
Carla Puca

BSc, MPH, MIDI

Dr Minda Sarna
Dr Minda Sarna

M.App.Epid., PhD

Senior Research Officer

Huong Le
Huong Le

MA (Dev. Econ), MA (App. Stats), PhD (Econ)

Biostatistician & Data Analyst

Honorary Team Member

Carolyn Finucane

Carolyn Finucane

Research Nurse

Cathy Pienaar

Cathy Pienaar

Honorary Team Member

Charlie Holland

Charlie Holland

PhD Student

Damien Foo

Damien Foo

Research Officer

Daniel Oakes

Daniel Oakes

PhD Student

Dhruv Shah

Dhruv Shah

Program Manager, Infectious Diseases Epidemiology Team

Fiona Giannini

Fiona Giannini

Mathematical Modeller

Joanne Harvey

Joanne Harvey

Clinical Trial Coordinator

Kate Britton

Kate Britton

PhD Student

Leslie-Ann Conway

Leslie-Ann Conway

Honorary Team Member

Muna Jibril

Muna Jibril

Student

Zoe Clarke

Zoe Clarke

Project Coordinator

Australian Group on Antimicrobial Resistance surveillance outcome programs - bloodstream infections and antimicrobial resistance patterns in Australian children and adolescents 2022 - 2023

Between January 2022 and December 2023, there were 1,827 bloodstream infection (BSI) isolates in 1,745 children and adolescents reported to the Australian Group on Antimicrobial Resistance (AGAR) surveillance outcome programs, with 40% of episodes in children aged < 12 months. 

Neonatal and infant mortality after maternal influenza and pertussis vaccination: Probabilistically linked cohort study

Maternal influenza and pertussis vaccination is an important strategy to reduce morbidity and mortality in infants. Previous vaccine safety studies have mostly focused on the association between maternal vaccination and fetal death.

Drug-resistant gram-negative bacterial infections in children in the Oceania region: review of the epidemiology, antimicrobial availability, treatment, clinical trial and pharmacokinetic

Gram-negative bacterial infections remain a major cause of morbidity and mortality in children and neonates globally, compounded by the rise of antimicrobial resistance. Barriers to paediatric antibiotic licencing lead to reduced availability of potentially effective agents for treatment. For children and neonates in the Oceania region, specific challenges remain including a paucity of surveillance data on local rates of antimicrobial resistance, and lack of availability of newer, more costly agents.

Predicting regional and temporal incidence of RSV and influenza hospitalizations in a birth cohort of young Australian children

Western Australia experiences multiple climatic zones, influencing the epidemiology of respiratory viruses. We aimed to estimate the true incidence of respiratory syncytial virus and influenza hospitalizations across these different climatic regions using predictive modelling.

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Infectious Diseases Epidemiology

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